Ddh335 3127..3138
نویسندگان
چکیده
Genome Damage and Stability Centre, University of Sussex, East Sussex, BN1 9RQ, UK, Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, NL-1081 BT, Amsterdam, The Netherlands, Institute of Human Genetics, Charite-University Medicine Berlin, Augustenburger platz 1, Berlin 13353, Germany and Institute of Human Genetics, University of Aarhus, The Bartholin Building, DK-8000 Aarhus C, Denmark
منابع مشابه
MicroRNA-3127 promotes cell proliferation and tumorigenicity in hepatocellular carcinoma by disrupting of PI3K/AKT negative regulation
Recent studies have shown that multiple phosphatases deactivate the PI3K/AKT signaling pathway. Here we demonstrated that, by suppressing multiple phosphatases, miR-3127 promotes growth of hepatocellular carcinoma (HCC). Our study also reveals clinical significance of miR-3127 expression in HCC patients. MiR-3127 expression was markedly upregulated in HCC tissues and cells. Furthermore, high mi...
متن کاملReduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway
miR-3127-5p is a primate-specific miRNA which is down-regulated in recurrent NSCLC tissue vs. matched primary tumor tissue (N = 15) and in tumor tissue vs. normal lung tissue (N = 177). Reduced miR-3127-5p expression is associated with a higher Ki-67 proliferation index and unfavorable prognosis in NSCLC. Overexpression of miR-3127-5p significantly reduced NSCLC cells proliferation, migration, ...
متن کاملRadio Properties of the Shapley Concentration . II . J 1324 − 3138 : a remnant of a radio galaxy in the Abell cluster A 3556 ?
In this paper we present a detailed study of the radio galaxy J1324−3138, located at a projected distance of 2 ′ from the centre of the Abell cluster of galaxies A3556, belonging to the core of the Shapley Concentration, at an average redshift z=0.05. We have observed J1324−3138 over a wide range of frequencies: Our analysis suggests that J1324−3138 is a remnant of a tailed radio galaxy, in whi...
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Over the prior two decades, imiquimod, a toll-like receptor 7 agonist, has been applied to nearly 50 clinical settings. Because of its immunomodulatory role, the topical cream today, for the first time, is being applied to cutaneous breast cancer in preclinical models and in a phase II clinical trial.
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